10鏈?5鏃ワ紝鍥藉鍗仴濮旂鎶€鏁欒偛鍙擱€氭姤浜?6璧峰尰瀛︾鐮旇瘹淇℃浠惰皟鏌ュ鐞嗙粨鏋溿€?/p>

涓€銆佹箹鍖楃渷鎭╂柦鍦熷鏃忚嫍鏃忚嚜娌誨窞涓績鍖婚櫌寰愯壋鍗庝負閫氳浣滆€咃紝鍛ㄧ濯涗負絎竴浣滆€呭彂琛ㄧ殑璁烘枃“MiR-221 affects proliferation and apoptosis of gastric cancer cells through targeting SOCS3”緇忔煡錛岃璁烘枃絎竴浣滆€呭懆縐嬪獩瀛樺湪涔板崠鏁版嵁銆佺紪閫犵爺絀惰繃紼嬬殑瀛︽湳涓嶇琛屼負錛岄€氳浣滆€呭緪鑹沖崕瀛樺湪涓嶆褰撶講鍚嶇殑瀛︽湳涓嶇琛屼負銆傚鐩稿叧璐ｄ換浜轟綔鍑哄涓嬪鐞嗭細

1.瀵圭涓€浣滆€呭懆縐嬪獩錛氱鐮旇瘹淇¤鍕夎皥璇濓紱鍦ㄥ尰闄㈠懆浼氫笂閫氭姤鎵硅瘎錛涗簲騫村唴涓嶅緱鏅嬭亴鏅嬪崌錛岄€€鍑烘仼鏂藉窞涓績鍖婚櫌闈掑勾浜烘墠鎴愰暱宸ョ▼錛岄€€鍥炴鏂囩珷鎵€寰楀尰闄㈠鍔憋紱鎾ょ錛涘彇娑堟湰騫村害璇勫厛琛ㄦā璧勬牸銆?/p>

2.瀵歸€氳浣滆€呭緪鑹沖崕錛氱鐮旇瘹淇¤鍕夎皥璇濓紝閫氭姤鎵硅瘎錛屼竴騫村唴涓嶅緱鏅嬭亴鏅嬪崌錛屽彇娑堟湰騫村害璇勫厛琛ㄦā璧勬牸銆?/p>

浜屻€佸北涓滅渷涓存矀甯備腑蹇冨尰闄警浠曟尟涓虹涓€浣滆€呫€佺▼瀛愭槑涓洪€氳浣滆€呭彂琛ㄨ鏂?ldquo;Ailanthone exerts an antitumor function on thedevelopment of human lung cancer by upregulating microRNA鈥?95”錛岀粡鏌ワ紝緋誨瓨鍦ㄨ鏂囦拱鍗栫殑瀛︽湳涓嶇琛屼負錛屼笖鎶曠鍓嶆湭鎸夎鑼冪▼搴忚幏寰楁墍鏈変綔鑰呯煡鎯呴€氱煡銆傚鐩稿叧璐ｄ換浜哄憳浣滃嚭濡備笅澶勭悊錛?/p>

1.瀵圭涓€浣滆€呬警浠曟尟錛氱鐮旇瘹淇¤鍕夎皥璇濓紝璐ｆ垚鍏跺啓鍑轟功闈㈡鏌ワ紱鍏ㄩ櫌閫氭姤鎵硅瘎錛涘彇娑堝叾鍙傚姞2020騫村害璇勫厛鏍戜紭錛屽勾搴﹁€冩牳涓嶅緱紜畾涓轟紭縐€絳夋錛涘彇娑堝叾6騫村唴縐戠爺欏圭洰銆佺鐮斿鍔便€佺鎶€鎴愭灉銆佺鎶€浜烘墠璁″垝絳夌敵鎶ヨ祫鏍鹼紱鍙栨秷鍏?騫村唴浣滀負鎻愬悕鎴栨帹鑽愪漢銆佽鎻愬悕鎴栨帹鑽愪漢銆佽瘎瀹′笓瀹剁瓑璧勬牸錛涙殏鍋滃叾鐮旂┒鐢熷甯堢敵璇瘋祫鏍?騫達紱瑕佹眰鍏?0澶╁唴鑱旂郴鏉傚織紺炬挙紼匡紱緗氭5000鍏冦€?/p>

2.瀵歸€氳浣滆€呯▼瀛愭槑錛氱鐮旇瘹淇¤鍕夎皥璇濓紝璐ｆ垚鍏跺啓鍑轟功闈㈡鏌ワ紱鍏ㄩ櫌閫氭姤鎵硅瘎錛涘彇娑堝叾鍙傚姞2020騫村害璇勫厛鏍戜紭錛屽勾搴﹁€冩牳涓嶅緱紜畾涓轟紭縐€絳夋錛涘彇娑堝叾1騫村唴縐戠爺欏圭洰銆佺鐮斿鍔便€佺鎶€鎴愭灉銆佺鎶€浜烘墠璁″垝絳夌敵鎶ヨ祫鏍鹼紱鍙栨秷鍏?騫村唴浣滀負鎻愬悕鎴栨帹鑽愪漢銆佽鎻愬悕鎴栨帹鑽愪漢銆佽瘎瀹′笓瀹剁瓑璧勬牸錛涙殏鍋滃叾鐮旂┒鐢熷甯堢敵璇瘋祫鏍?騫達紱瑕佹眰鍏?0澶╁唴鑱旂郴鏉傚織紺炬挙紼褲€?/p>

3.瀵瑰叾浠栦綔鑰呯帇鏂囩幉銆佺帇鍚戜笢銆佹鐜夊叺錛氱鐮旇瘹淇¤鍕夎皥璇濓紝闄㈠唴閫氭姤鎵硅瘎銆?/p>

涓夈€佸北涓滅渷涓存矀甯備腑蹇冨尰闄㈣淳娣戠帀涓虹涓€浣滆€呫€佸紶椋炰負閫氳浣滆€呭彂琛ㄨ鏂?ldquo;MicroRNA-210 protects against periodontitis through targeting HIF-3α and inhibiting p38MAPK/NF-κB pathway”錛岀粡鏌ワ紝緋誨瓨鍦ㄨ鏂囦拱鍗栫殑瀛︽湳涓嶇琛屼負錛屼笖鎶曠鍓嶆湭鎸夎鑼冪▼搴忚幏寰楁墍鏈変綔鑰呯煡鎯呴€氱煡銆傚鐩稿叧璐ｄ換浜哄憳浣滃嚭濡備笅澶勭悊錛?/p>

1.瀵圭涓€浣滆€呰淳娣戠帀錛氱鐮旇瘹淇¤鍕夎皥璇濓紝璐ｆ垚鍏跺啓鍑轟功闈㈡鏌ワ紱鍏ㄩ櫌閫氭姤鎵硅瘎錛涘彇娑堝叾鍙傚姞2020騫村害璇勫厛鏍戜紭錛屽勾搴﹁€冩牳涓嶅緱紜畾涓轟紭縐€絳夋錛涘彇娑堝叾5騫村唴縐戠爺欏圭洰銆佺鐮斿鍔便€佺鎶€鎴愭灉銆佺鎶€浜烘墠璁″垝絳夌敵鎶ヨ祫鏍鹼紱鍙栨秷鍏?騫村唴浣滀負鎻愬悕鎴栨帹鑽愪漢銆佽鎻愬悕鎴栨帹鑽愪漢銆佽瘎瀹′笓瀹剁瓑璧勬牸錛涙殏鍋滃叾鐮旂┒鐢熷甯堢敵璇瘋祫鏍?騫達紱瑕佹眰鍏?0澶╁唴鑱旂郴鏉傚織紺炬挙紼匡紱緗氭5000鍏冦€?/p>

2.瀵歸€氳浣滆€呭紶椋烇細縐戠爺璇氫俊璇媺璋堣瘽錛岃矗鎴愬叾鍐欏嚭涔﹂潰媯€鏌ワ紱鍏ㄩ櫌閫氭姤鎵硅瘎錛涘彇娑堝叾鍙傚姞2020騫村害璇勫厛鏍戜紭錛屽勾搴﹁€冩牳涓嶅緱紜畾涓轟紭縐€絳夋錛涘彇娑堝叾1騫村唴縐戠爺欏圭洰銆佺鐮斿鍔便€佺鎶€鎴愭灉銆佺鎶€浜烘墠璁″垝絳夌敵鎶ヨ祫鏍鹼紱鍙栨秷鍏?騫村唴浣滀負鎻愬悕鎴栨帹鑽愪漢銆佽鎻愬悕鎴栨帹鑽愪漢銆佽瘎瀹′笓瀹剁瓑璧勬牸錛涙殏鍋滃叾鐮旂┒鐢熷甯堢敵璇瘋祫鏍?騫達紱瑕佹眰鍏?0澶╁唴鑱旂郴鏉傚織紺炬挙紼褲€?/p>

3.瀵瑰叾浠栦綔鑰呮潹瑗跨編銆佹潹瑗胯崳錛氱鐮旇瘹淇¤鍕夎皥璇濓紝闄㈠唴閫氭姤鎵硅瘎銆?/p>

鍥涖€佸北涓滅渷涓存矀甯備腑蹇冨尰闄㈡垰寰峰嘲涓虹涓€浣滆€呫€佷簬椋庡崕涓洪€氳浣滆€呭彂琛ㄨ鏂?ldquo;Knockdown of lncRNA-H19 inhibits cell viability, migration and invasion T while promotes apoptosis via microRNA-143/RUNX2 axis in retinoblastoma”錛岀粡鏌ワ紝緋誨瓨鍦ㄨ鏂囦拱鍗栫殑瀛︽湳涓嶇琛屼負錛屼笖鎶曠鍓嶆湭鎸夎鑼冪▼搴忚幏寰楁墍鏈変綔鑰呯煡鎯呴€氱煡銆傚鐩稿叧璐ｄ換浜哄憳浣滃嚭濡備笅澶勭悊錛?/p>

1.瀵圭涓€浣滆€呮垰寰峰嘲錛氱鐮旇瘹淇¤鍕夎皥璇濓紝璐ｆ垚鍏跺啓鍑轟功闈㈡鏌ワ紱鍏ㄩ櫌閫氭姤鎵硅瘎錛涘彇娑堝叾鍙傚姞2020騫村害璇勫厛鏍戜紭錛屽勾搴﹁€冩牳涓嶅緱紜畾涓轟紭縐€絳夋錛涘彇娑堝叾5騫村唴縐戠爺欏圭洰銆佺鐮斿鍔便€佺鎶€鎴愭灉銆佺鎶€浜烘墠璁″垝絳夌敵鎶ヨ祫鏍鹼紱鍙栨秷鍏?騫村唴浣滀負鎻愬悕鎴栨帹鑽愪漢銆佽鎻愬悕鎴栨帹鑽愪漢銆佽瘎瀹′笓瀹剁瓑璧勬牸錛涙殏鍋滃叾鐮旂┒鐢熷甯堢敵璇瘋祫鏍?騫達紱鎾ら攢鍏跺埄鐢ㄧ鐮斿け淇¤涓鴻幏寰楀壇涓諱換鍖誨笀鑱岀О璧勬牸錛涜姹傚叾30澶╁唴鑱旂郴鏉傚織紺炬挙紼匡紱緗氭5000鍏冦€?/p>

2.瀵歸€氳浣滆€呬簬椋庡崕錛氱鐮旇瘹淇¤鍕夎皥璇濓紝璐ｆ垚鍏跺啓鍑轟功闈㈡鏌ワ紱鍏ㄩ櫌閫氭姤鎵硅瘎錛涘彇娑堝叾鍙傚姞2020騫村害璇勫厛鏍戜紭錛屽勾搴﹁€冩牳涓嶅緱紜畾涓轟紭縐€絳夋銆傚彇娑堝叾2騫村唴縐戠爺欏圭洰銆佺鐮斿鍔便€佺鎶€鎴愭灉銆佺鎶€浜烘墠璁″垝絳夌敵鎶ヨ祫鏍鹼紱鍙栨秷鍏?騫村唴浣滀負鎻愬悕鎴栨帹鑽愪漢銆佽鎻愬悕鎴栨帹鑽愪漢銆佽瘎瀹′笓瀹剁瓑璧勬牸錛涙殏鍋滃叾鐮旂┒鐢熷甯堢敵璇瘋祫鏍?騫達紱瑕佹眰鍏?0澶╁唴鑱旂郴鏉傚織紺炬挙紼褲€?/p>

3.鍏朵粬浣滆€呯帇鏄庢槑錛氫負闈掑矝甯傚煄闃沖尯浜烘皯鍖婚櫌鑱屽伐錛岄潚宀涘競鍩庨槼鍖轟漢姘戝尰闄㈢粰浜堢帇鏄庢槑錛氱鐮旇瘹淇¤鍕夎皥璇濓紝鍙栨秷2020騫村害璇勫厛鏍戜紭璧勬牸銆?/p>

浜斻€佸北涓滅渷涓存矀甯備腑蹇冨尰闄㈢涓€浣滆€呭緪寤恒€佽檔蹇楀涓洪€氳浣滆€呭彂琛ㄨ鏂?ldquo;Ras-ERK1/2signaling participates in the progression of  gastric cancer through repressing Aurora-B-mediated H1.4 phoshorylation at Ser27”錛岀粡鏌ワ紝緋誨瓨鍦ㄨ鏂囦拱鍗栫殑瀛︽湳涓嶇琛屼負錛屼笖鎶曠鍓嶆湭鎸夎鑼冪▼搴忚幏寰楁墍鏈変綔鑰呯煡鎯呴€氱煡銆傚鐩稿叧璐ｄ換浜哄憳浣滃嚭濡備笅澶勭悊錛?/p>

1.瀵圭涓€浣滆€呭緪寤猴細縐戠爺璇氫俊璇媺璋堣瘽錛岃矗鎴愬叾鍐欏嚭涔﹂潰媯€鏌ワ紱鍏ㄩ櫌閫氭姤鎵硅瘎錛涘彇娑堝叾鍙傚姞2020騫村害璇勫厛鏍戜紭錛屽勾搴﹁€冩牳涓嶅緱紜畾涓轟紭縐€絳夋錛涘彇娑堝叾5騫村唴縐戠爺欏圭洰銆佺鐮斿鍔便€佺鎶€鎴愭灉銆佺鎶€浜烘墠璁″垝絳夌敵鎶ヨ祫鏍鹼紱鍙栨秷鍏?騫村唴浣滀負鎻愬悕鎴栨帹鑽愪漢銆佽鎻愬悕鎴栨帹鑽愪漢銆佽瘎瀹′笓瀹剁瓑璧勬牸錛涙殏鍋滃叾鐮旂┒鐢熷甯堢敵璇瘋祫鏍?騫達紱瑕佹眰鍏?0澶╁唴鑱旂郴鏉傚織紺炬挙紼匡紱緗氭5000鍏冦€?/p>

2.瀵歸€氳浣滆€呰檔蹇楀錛氱鐮旇瘹淇¤鍕夎皥璇濓紝璐ｆ垚鍏跺啓鍑轟功闈㈡鏌ワ紱鍏ㄩ櫌閫氭姤鎵硅瘎錛涘彇娑堝叾鍙傚姞2020騫村害璇勫厛鏍戜紭錛屽勾搴﹁€冩牳涓嶅緱紜畾涓轟紭縐€絳夋錛涘彇娑堝叾1騫村唴縐戠爺欏圭洰銆佺鐮斿鍔便€佺鎶€鎴愭灉銆佺鎶€浜烘墠璁″垝絳夌敵鎶ヨ祫鏍鹼紱鍙栨秷鍏?騫村唴浣滀負鎻愬悕鎴栨帹鑽愪漢銆佽鎻愬悕鎴栨帹鑽愪漢銆佽瘎瀹′笓瀹剁瓑璧勬牸錛涙殏鍋滃叾鐮旂┒鐢熷甯堢敵璇瘋祫鏍?騫達紱瑕佹眰鍏?0澶╁唴鑱旂郴鏉傚織紺炬挙紼褲€?/p>

3.瀵瑰叾浠栦綔鑰呯敯宄般€侀檲鍏寸敯銆佸垬鍏嗛湠銆佹浼犻湠錛氱鐮旇瘹淇¤鍕夎皥璇濓紝闄㈠唴閫氭姤鎵硅瘎銆?/p>

鍏€佸北涓滅渷闈掑矝甯傜鍏漢姘戝尰闄㈠瓩鏍戜雞涓洪€氳浣滆€咃紝浜庨洩銆佺帇鐜変負騫跺垪絎竴浣滆€呭彂琛ㄧ殑璁烘枃“Geniposide plays anti-tumor effects by down-regulation of microRNA-224 in HepG2 and Huh7 cell lines”錛岀粡鏌ワ紝緋誨瓨鍦ㄨ鏂囦唬鍐欎唬鎶曠殑瀛︽湳涓嶇琛屼負銆傞潚宀涘競絎叚浜烘皯鍖婚櫌瀵歸€氳浣滆€呭瓩鏍戜雞銆佺涓€浣滆€呬簬闆強騫跺垪絎竴浣滆€呯帇鐜変綔鍑哄涓嬪鐞嗭細縐戠爺璇氫俊璇媺璋堣瘽錛岄€氭姤鎵硅瘎錛屽彇娑堜簲騫村唴鐢寵鎴栫敵鎶ョ鎶€璁″垝欏圭洰(涓撻」銆佸熀閲戠瓑)銆佺鎶€濂栧姳銆佺鎶€浜烘墠縐板彿鍜屼笓涓氭妧鏈亴鍔℃檵鍗囩瓑璧勬牸錛屽彇娑堝浼氥€佸崗浼氥€佺爺絀朵細絳夊鏈洟浣撲互鍙婂鏈€佸浣嶅鍛樹細絳夊鏈伐浣滄満鏋勭殑濮斿憳鎴栨垚鍛樿祫鏍鹼紝鍙栨秷浜斿勾鍐呬綔涓烘彁鍚嶆垨鎺ㄨ崘浜恒€佽鎻愬悕鎴栨帹鑽愪漢銆佽瘎瀹′笓瀹剁瓑璧勬牸錛屾挙紼褲€?/p>

涓冦€佸北涓滅渷闈掑矝甯傛搗鎱堝尰鐤楅泦鍥㈡洸鏇奸潚涓洪€氳浣滆€呫€佸紶鍠滃啗涓虹涓€浣滆€呭彂琛ㄧ殑璁烘枃“Angelica polysaccharide alleviates oxidative response damage in HaCaT cells through up-regulation of miR-126”錛岀粡鏌ワ紝緋誨瓨鍦ㄧ鏀規暟鎹€佺紪閫犵爺絀惰繃紼嬨€佷笉褰撶講鍚嶇殑瀛︽湳涓嶇琛屼負銆傚鐩稿叧璐ｄ換浜哄憳浣滃嚭濡備笅澶勭悊錛?/p>

1.瀵圭涓€浣滆€呭紶鍠滃啗銆侀€氳浣滆€呮洸鏇奸潚錛氱鐮旇瘹淇¤鍕夎皥璇濓紝闄㈠唴鍏紑閫氭姤鎵硅瘎錛岀珛鍗寵仈緋繪潅蹇楃ぞ鎾ょ娑変簨璁烘枃錛屽彇娑堜簲騫寸敵璇鋒垨鐢蟲姤縐戞妧璁″垝欏圭洰銆佺鎶€濂栧姳銆佺鎶€浜烘墠縐板彿璧勬牸錛屽彇娑堜簲騫翠笓涓氭妧鏈亴鍔℃檵鍗囪祫鏍箋€?/p>

2.瀵圭浜屼綔鑰呰枦綰€佺涓変綔鑰呭懆钀嶃€佺鍥涗綔鑰呭垬涓姐€佺浜斾綔鑰呬簬鏅躲€佺鍏綔鑰呬唬鏈嬮錛氱鐮旇瘹淇¤鍕夎皥璇濓紝闄㈠唴鍏紑閫氭姤鎵硅瘎錛屽彇娑堜竴騫寸敵璇鋒垨鐢蟲姤縐戞妧璁″垝欏圭洰銆佺鎶€濂栧姳銆佺鎶€浜烘墠縐板彿璧勬牸錛屽彇娑堜竴騫翠笓涓氭妧鏈亴鍔℃檵鍗囪祫鏍箋€?/p>

鍏€佸北涓滅渷闈掑矝甯傛搗鎱堝尰鐤楅泦鍥㈢帇嫻烽潤涓洪€氳浣滆€呫€侀偣鐝轟負絎竴浣滆€呭彂琛ㄧ殑璁烘枃“Euxanthone Inhibits Glycolysis and Triggers Mitochondria-Mediated Apoptosis by Targeting Hexokinase 2 in Epithelial Ovarian Cancer”錛岀粡鏌ワ紝緋誨瓨鍦ㄧ鏀規暟鎹€佺紪閫犵爺絀惰繃紼嬨€佷笉褰撶講鍚嶇殑瀛︽湳涓嶇琛屼負銆傚鐩稿叧璐ｄ換浜哄憳浣滃嚭濡備笅澶勭悊錛?/p>

1.瀵圭涓€浣滆€呴偣鐝猴細縐戠爺璇氫俊璇媺璋堣瘽錛岄櫌鍐呭叕寮€閫氭姤鎵硅瘎錛岀珛鍗寵仈緋繪潅蹇楃ぞ鎾ょ娑変簨璁烘枃錛屾敹鍥炵鐮斿鍔憋紝鍙栨秷浜斿勾鐢寵鎴栫敵鎶ョ鎶€璁″垝欏圭洰銆佺鎶€濂栧姳銆佺鎶€浜烘墠縐板彿璧勬牸錛屽彇娑堜簲騫翠笓涓氭妧鏈亴鍔℃檵鍗囪祫鏍鹼紝鍙栨秷鐢辨鑾峰緱鐨勫壇楂樼駭鑱岀О銆?/p>

2.瀵歸€氳浣滆€呯帇嫻烽潤錛氱鐮旇瘹淇¤鍕夎皥璇濓紝闄㈠唴鍏紑閫氭姤鎵硅瘎錛岀珛鍗寵仈緋繪潅蹇楃ぞ鎾ょ娑変簨璁烘枃錛屽彇娑堜簲騫寸敵璇鋒垨鐢蟲姤縐戞妧璁″垝欏圭洰銆佺鎶€濂栧姳銆佺鎶€浜烘墠縐板彿璧勬牸錛屽彇娑堜簲騫翠笓涓氭妧鏈亴鍔℃檵鍗囪祫鏍箋€?/p>

3.瀵圭浜屼綔鑰呯帇浜氭銆佺浜斾綔鑰呴儜鏂囧緩銆佺鍏綔鑰呴珮鑼滐細縐戠爺璇氫俊璇媺璋堣瘽錛岄櫌鍐呭叕寮€閫氭姤鎵硅瘎錛屽彇娑堜竴騫寸敵璇鋒垨鐢蟲姤縐戞妧璁″垝欏圭洰銆佺鎶€濂栧姳銆佺鎶€浜烘墠縐板彿璧勬牸錛屽彇娑堜竴騫翠笓涓氭妧鏈亴鍔℃檵鍗囪祫鏍箋€?/p>

4.瀵圭涓変綔鑰呭垬鏄庡ǎ錛氱鐮旇瘹淇¤鍕夎皥璇濓紝闄㈠唴鍏紑閫氭姤鎵硅瘎錛屽彇娑堜竴騫寸敵璇鋒垨鐢蟲姤縐戞妧璁″垝欏圭洰銆佺鎶€濂栧姳銆佺鎶€浜烘墠縐板彿璧勬牸錛屽彇娑堜竴騫翠笓涓氭妧鏈亴鍔℃檵鍗囪祫鏍鹼紝鍙栨秷涓駭鑱岀О銆?/p>

涔濄€佸北涓滅渷闈掑矝甯備腑蹇冨尰闄㈤粠鑻辮豹涓洪€氳浣滆€咃紝鏉ㄥ瓭鑹涓€浣滆€呭彂琛ㄧ殑璁烘枃“Baicalein restrains proliferation, migration, and invasion of human malignant melanoma cells by down-regulating colon cancer associated transcript-1”錛岀粡鏌ワ紝緋誨瓨鍦ㄧ鏀瑰疄楠屾暟鎹殑瀛︽湳涓嶇琛屼負銆傚鐩稿叧璐ｄ換浜轟綔鍑哄涓嬪鐞嗭細

1.瀵歸€氳浣滆€呴粠鑻辮豹錛氱鐮旇瘹淇¤鍕夎皥璇濓紝闄㈠唴鍏紑閫氭姤鎵硅瘎錛岃拷鍥炴枃绔犲鍔卞茍瑕佹眰鍏朵富鍔ㄥ悜鏉傚織紺炬挙鍥炴枃绔狅紝鍙栨秷鍏朵簲騫寸敵鎶ョ鐮旈」鐩€佺鎶€濂栧姳銆佺鎶€浜烘墠縐板彿鍜岃亴縐版檵鍗囪祫鏍箋€?/p>

2.瀵圭涓€浣滆€呮潹瀛濊壇錛氱鐮旇瘹淇¤鍕夎皥璇濓紝闄㈠唴鍏紑閫氭姤鎵硅瘎錛屽彇娑堝叾浜斿勾鐢蟲姤縐戠爺欏圭洰銆佺鎶€濂栧姳銆佺鎶€浜烘墠縐板彿鍜岃亴縐版檵鍗囪祫鏍箋€?/p>

3.瀵圭浜屼綔鑰呭媧ユ澃銆佺涓変綔鑰呭紶鏄ヨ壋錛氱鐮旇瘹淇¤鍕夎皥璇濓紝闄㈠唴鍏紑閫氭姤鎵硅瘎錛屽彇娑堝叾浜屽勾鐢蟲姤縐戠爺欏圭洰銆佺鎶€濂栧姳銆佺鎶€浜烘墠縐板彿鍜岃亴縐版檵鍗囪祫鏍箋€?/p>

鍗併€佹渤鍗楃渷浜烘皯鍖婚櫌鏉ㄥ織鍒氫負閫氳浣滆€呫€佹潕鏅撲寒涓虹涓€浣滆€呭彂琛ㄧ殑璁烘枃“Silence of MEG3 intensifies lipopolysaccharide-stimulated damage of human lung cells through modulating miR-4262”錛岀粡鏌ワ紝緋誨瓨鍦ㄧ涓夋柟鏈烘瀯鎻愪緵瀹為獙鍥劇墖鍜屽疄楠屾暟鎹?涔板崠鏁版嵁)鐨勫鏈笉绔涓恒€傚鐩稿叧璐ｄ換浜轟綔鍑哄涓嬪鐞嗭細

1.瀵圭涓€浣滆€呮潕鏅撲寒錛氱鐮旇瘹淇¤鍕夎皥璇濓紝鍏ㄩ櫌鍏紑閫氭姤鎵硅瘎錛屽彇娑堣瘎浼樿瘎鍏堣祫鏍?騫達紝鍙栨秷鐢蟲姤鐮旂┒鐢熷甯堣祫鏍兼垨鏆傚仠鎷涙敹鐮旂┒鐢?騫達紝鍙栨秷鐢寵鎴栫敵鎶ョ鎶€璁″垝欏圭洰(涓撻」銆佸熀閲戠瓑)銆佺鎶€濂栧姳銆佺鎶€浜烘墠縐板彿鍜屼笓涓氭妧鏈亴鍔℃檵鍗囩瓑璧勬牸5騫達紝鎾ょ銆?/p>

2.瀵歸€氳浣滆€呮潹蹇楀垰錛氱鐮旇瘹淇¤鍕夎皥璇濓紝鍙栨秷褰撳勾璇勪紭璇勫厛璧勬牸銆?/p>

鍗佷竴銆佹渤鍗楃渷浜烘皯鍖婚櫌宕旀窇濞翠負閫氳浣滆€呫€佹潕鐜蹭負絎竴浣滆€呭彂琛ㄧ殑璁烘枃“Baicalin relieves TNF-alpha-evoked injury in human aortic endothelial cells by up-regulation of miR-145”錛岀粡鏌ワ紝緋誨瓨鍦ㄧ涓夋柟鏈烘瀯鎻愪緵瀹為獙鍥劇墖鍜屽疄楠屾暟鎹?涔板崠鏁版嵁)騫朵唬涓烘姇紼跨殑瀛︽湳涓嶇琛屼負銆傚鐩稿叧璐ｄ換浜轟綔鍑哄涓嬪鐞嗭細

1.瀵圭涓€浣滆€呮潕鐜詫細縐戠爺璇氫俊璇媺璋堣瘽錛屽叏闄㈠叕寮€閫氭姤鎵硅瘎錛屽彇娑堣瘎浼樿瘎鍏堣祫鏍?騫達紝鍙栨秷鐢蟲姤鐮旂┒鐢熷甯堣祫鏍兼垨鏆傚仠鎷涙敹鐮旂┒鐢?騫達紝鍙栨秷鐢寵鎴栫敵鎶ョ鎶€璁″垝欏圭洰(涓撻」銆佸熀閲戠瓑)銆佺鎶€濂栧姳銆佺鎶€浜烘墠縐板彿鍜屼笓涓氭妧鏈亴鍔℃檵鍗囩瓑璧勬牸5騫達紝鎾ょ銆?/p>

2.瀵歸€氳浣滆€呭磾娣戝ù錛氱鐮旇瘹淇¤鍕夎皥璇濓紝鍙栨秷褰撳勾璇勪紭璇勫厛璧勬牸銆?/p>

3.瀵瑰叾浠栫浉鍏充綔鑰呭垬鏁忋€佽但榪炴浖銆佺帇鐝婄強錛氱鐮旇瘹淇¤鍕夎皥璇濄€?/p>

鍗佷簩銆佹睙鑻忕渷鍗椾含鍖葷澶у鍦ㄨ亴涓撲笟瀛︿綅鐮旂┒鐢熸矆椋炰負絎竴浣滆€呭彂琛ㄧ殑璁烘枃“Amentoflavone Promotes Apoptosis in Non-small Cell Lung Cancer by Modulating Cancerous Inhibitor of PP2A”錛岀粡鏌ワ紝緋誨瓨鍦ㄤ吉閫犲強綃℃敼鏁版嵁銆佹湭緇忛€氳浣滆€呭強鍏朵粬浣滆€呭悓鎰忕講鍏跺悕銆佸鎵樼涓夋柟浠ｆ姇璁烘枃鐨勫鏈笉绔涓恒€?/p>

1.鍗椾含鍖葷澶у瀵圭浉鍏寵矗浠諱漢鍛樹綔鍑哄鐞嗭紝鎾ら攢娌堥鍗氬＋瀛︿綅錛屾殏鍋滅涓€闄勫睘鍖婚櫌閫氳浣滆€呴檲浜︽睙鐮旂┒鐢熸嫑鐢熻祫鏍?騫淬€?/p>

2.絎竴浣滆€呭伐浣滃崟浣嶆睙闃村競浜烘皯鍖婚櫌緇欎簣娌堥琛屾斂璀﹀憡澶勫垎錛屽叏闄㈤€氭姤鎵硅瘎錛?騫村唴鍙栨秷鐢寵鎴栫敵鎶ュ悇綾葷鎶€璁″垝欏圭洰銆佷漢鎵嶇О鍙瘋祫鏍鹼紝鍙栨秷涓撲笟鎶€鏈亴鍔℃檵鍗?騫淬€?/p>

鍗佷笁銆佹睙鑻忕渷姹熼槾甯備漢姘戝尰闄€佸崡浜尰縐戝ぇ瀛﹂檮灞為€稿か鍖婚櫌鍦ㄨ亴鍗氬＋鐮旂┒鐢熸柟閾負絎竴浣滆€咃紝鍙戣〃浜嶵HE ANATOMICAL RECORD鏉傚織鐨勮鏂?ldquo;Alpinumisoflavone Inhibits Tumor Growth and Metastasis in Papillary Thyroid Cancer via Upregulating miR鈥?41鈥?p”錛岀粡鏌ワ紝緋葷敱絎竴浣滆€呮柟閾鑷姇紼匡紝瀛樺湪浼€犻偖綆便€佷笉褰撶講鍚嶇瓑瀛︽湳涓嶇琛屼負銆?/p>

姹熼槾甯備漢姘戝尰闄㈠強鍗椾含鍖葷澶у鍙婂鐩稿叧璐ｄ換浜轟綔鍑哄涓嬪鐞嗭細鎾ら攢絎竴浣滆€呮柟閾崥澹浣嶏紝鍙栨秷鍏剁敵鎶ュ悇綰х鎶€璁″垝欏圭洰銆佷笓涓氭妧鏈亴縐版檵鍗囩瓑璧勬牸8騫?娑夊強鍏朵粬瀛︽湳涓嶇琛屼負錛屽悎騫跺緗?錛涙殏鍋滃甯堝垬鐓滀笓涓氬浣嶅崥澹爺絀剁敓鎷涙敹璧勬牸3騫淬€?/p>

鍗佸洓銆佹睙鑻忕渷鏃犻敗甯傚騫間繚鍋ラ櫌鍘熸楠岀璁擱涓洪€氳浣滆€呫€佹棤閿″競涓尰鍖婚櫌涓佸繝闃充負絎竴浣滆€呭彂琛ㄧ殑璁烘枃“Physcion 8-O-β-glucopyranoside prevents hypoxia-induced epithelial-mesenchymal transition in colorectal cancer HCT116 cells by modulating EMMPRIN”錛岀粡鏌ワ紝緋誨瓨鍦ㄥ鎵樼涓夋柟浠ｅ啓銆佷唬鎶曠殑瀛︽湳涓嶇琛屼負銆傝椋炰簬2017騫村洜鍏朵粬緇忔祹妗堜歡琚垽澶勪笁騫存湁鏈熷緬鍒戯紝鏃犻敗甯傚騫間繚鍋ラ櫌浜?018騫村皢鍏跺紑闄ゅ鍒嗐€傛棤閿″競涓尰鍖婚櫌瀵逛竵蹇犻槼鍋氬嚭濡備笅澶勭悊錛氱鐮旇鍕夎皥璇濓紝榪藉洖鍙戞斁鐨勭鐮斿鍔憋紝鍙栨秷鍚勭駭鍚勭被縐戞妧璁″垝欏圭洰(涓撻」銆佸熀閲戠瓑)銆佸悇綾諱漢鎵嶇О鍙峰拰涓撲笟鎶€鏈亴鍔℃檵鍗囩瓑璧勬牸5騫淬€?/p>

鍗佷簲銆佸崡閫氬競涓尰闄㈠柣嫻峰繝浣滀負閫氳浣滆€呫€佸崡閫氬競鑲跨槫鍖婚櫌鑲栨槬綰負鍏卞悓閫氳浣滆€咃紝鍗楅€氬競涓尰闄㈡浌綰㈣壋涓虹涓€浣滆€咃紝鍙戣〃鐨勮鏂?ensp;“miR-129 reduces CDDP resistance in gastric cancer cells by inhibiting MAPK3”錛岀粡鏌ワ紝鑲栨槬綰綔涓哄叡鍚岄€氳浣滆€咃紝瀛樺湪榪濊浣跨敤浜嗗熀閲戝彿“No.MS12017017-4”銆佺鏀規暟鎹殑瀛︽湳涓嶇琛屼負銆?/p>

1.鍗楅€氬競鑲跨槫鍖婚櫌瀵歸€氳浣滆€呰倴鏄ョ孩浣滃嚭濡備笅澶勭悊錛氭殏鍋滅敵鎶ヨ儲鏀胯祫鍔╃鎶€璁″垝(涓撻」銆佸熀閲戠瓑)欏圭洰絳夎祫鏍?騫達紝榪藉洖鐩稿叧璁烘枃濂栧姳錛岄€氭姤鎵硅瘎銆?/p>

2.鍗楅€氬競涓尰闄㈠鐩稿叧璐ｄ換浜轟綔鍑哄涓嬪鐞嗭細

(1)瀵歸€氳浣滆€呭柣嫻峰繝錛氶€氭姤鎵硅瘎錛屾挙紼匡紝鍙栨秷鐢蟲姤璐㈡斂璧勫姪縐戞妧璁″垝(涓撻」銆佸熀閲戠瓑)欏圭洰絳夎祫鏍?騫?鐗墊秹鍏朵粬璁烘枃閫犲亣錛屽悎騫跺緗?錛岃拷鍥炶鏂囦竴嬈℃€у閲戯紝鏁存敼鍜屽姞寮哄鏈洟闃熺鐞嗐€佸彇娑堝鏈鍛樹細濮斿憳璧勬牸銆?/p>

(2)瀵圭涓€浣滆€呮浌綰㈣壋錛氶€氭姤鎵硅瘎錛屾挙紼匡紝榪藉洖璁烘枃涓€嬈℃€у閲戯紝縐戠爺璇氫俊璇媺璋堣瘽錛屾暣鏀瑰拰鍔犲己瀛︽湳鍥㈤槦綆＄悊銆佸彇娑堝鏈鍛樹細濮斿憳璧勬牸銆?/p>

鍗佸叚銆佷腑鍥藉尰瀛︾瀛﹂櫌鍖椾含鍗忓拰鍖婚櫌宕旂帀灝氫負閫氳浣滆€呫€佸緪鏅撹緣涓虹涓€浣滆€呭彂琛ㄧ殑璁烘枃“MicroRNA-1246 inhibits cell invasion and epithelial mesenchymal transition process by  targeting CXCR4 in lung cancer cells”錛岀粡鏌ワ紝緋誨瓨鍦ㄨ鏂囧浘鐗囬€犲亣鐨勫鏈笉绔涓恒€傚鐩稿叧璐ｄ換浜哄憳浣滃嚭濡備笅澶勭悊錛?/p>

1銆佸閫氳浣滆€呭磾鐜夊皻錛氬彇娑堢敵鎶ョ鎶€璁″垝(涓撻」銆佸熀閲戠瓑)欏圭洰璧勬牸5騫達紝鍙栨秷鏅嬪崌鑱屽姟鑱岀О璧勬牸3騫達紝璁板叆縐戠爺璇氫俊淇＄敤淇℃伅緋葷粺錛岀鐮旇瘹淇¤鍕夎皥璇濈殑澶勭綒銆?/p>

2銆佸絎竴浣滆€呭緪鏅撹緣錛氬彇娑堢敵鎶ョ鎶€璁″垝(涓撻」銆佸熀閲戠瓑)欏圭洰璧勬牸5騫達紝鍙栨秷鏅嬪崌鑱屽姟鑱岀О璧勬牸3騫達紝璁板叆縐戠爺璇氫俊淇＄敤淇℃伅緋葷粺錛岃鍛婄殑澶勭綒銆?寮犺悓)

錛堣矗浠葷紪杈戯細瀛欏疂鍏夛級